Assay Detail
Binding
CHEMBL767149
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Inhibitory activity against human synovial recombinant Phospholipase enzyme
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Phospholipase A2, membrane associated (CHEMBL3474) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.61 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL109073 | — | — | 1 | 6.05 |
| CHEMBL463914 | MANOALIDE | — | 1 | 5.41 |
| CHEMBL109301 | — | — | 1 | 5.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL109073 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL463914 | MANOALIDE | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL109301 | — | IC50 | = | 4200.0 | nM | 5.38 |