Assay Detail
Binding
CHEMBL767220
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Inhibition of human neutrophil protein kinase C (PKC)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.14 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388978 | STAUROSPORINE | — | 1 | 8.60 |
| CHEMBL421565 | — | — | 1 | 8.32 |
| CHEMBL1202927 | — | — | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388978 | STAUROSPORINE | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL421565 | — | IC50 | = | 4.8 | nM | 8.32 |
| CHEMBL1202927 | — | IC50 | = | 32.0 | nM | 7.50 |