Assay Detail
Functional
CHEMBL767302
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at P2Y1 receptor measured as capacity to stimulate 50% phospholipase C in turkey erythrocyte membranes
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Meleagris gallopavo |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 10 | 5.47 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3144171 | — | — | 1 | 6.26 |
| CHEMBL1199057 | — | — | 1 | 6.19 |
| CHEMBL574817 | — | — | 1 | 5.89 |
| CHEMBL1161861 | — | — | 1 | 5.86 |
| CHEMBL1230817 | — | — | 1 | 5.20 |
| CHEMBL55804 | — | — | 1 | 5.08 |
| CHEMBL3144477 | — | — | 1 | 4.89 |
| CHEMBL1230695 | — | — | 1 | 4.39 |
| CHEMBL3144480 | — | — | 1 | - |
| CHEMBL608872 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3144171 | — | EC50 | = | 550.0 | nM | 6.26 |
| CHEMBL1199057 | — | EC50 | = | 651.0 | nM | 6.19 |
| CHEMBL574817 | — | EC50 | = | 1280.0 | nM | 5.89 |
| CHEMBL1161861 | — | EC50 | = | 1370.0 | nM | 5.86 |
| CHEMBL1230817 | — | EC50 | = | 6260.0 | nM | 5.20 |
| CHEMBL55804 | — | EC50 | = | 8330.0 | nM | 5.08 |
| CHEMBL3144477 | — | EC50 | = | 12900.0 | nM | 4.89 |
| CHEMBL1230695 | — | EC50 | = | 40900.0 | nM | 4.39 |
| CHEMBL3144480 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL608872 | — | EC50 | > | 100000.0 | nM | - |