Assay Detail
Binding
CHEMBL767439
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Inhibition of protein kinase C (PKC)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.62 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL345881 | — | — | 1 | 4.62 |
| CHEMBL345384 | — | — | 1 | - |
| CHEMBL156776 | — | — | 1 | - |
| CHEMBL347195 | — | — | 1 | - |
| CHEMBL347684 | — | — | 1 | - |
| CHEMBL154620 | — | — | 1 | - |
| CHEMBL3350557 | — | — | 1 | - |
| CHEMBL370100 | REBECCAMYCIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL345881 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL345384 | — | IC50 | > | 151000.0 | nM | - |
| CHEMBL156776 | — | IC50 | = | 101000.0 | nM | - |
| CHEMBL347195 | — | IC50 | > | 161000.0 | nM | - |
| CHEMBL347684 | — | IC50 | > | 162000.0 | nM | - |
| CHEMBL154620 | — | IC50 | > | 144000.0 | nM | - |
| CHEMBL3350557 | — | IC50 | > | 142000.0 | nM | - |
| CHEMBL370100 | REBECCAMYCIN | IC50 | > | 175000.0 | nM | - |