Assay Detail
Binding
CHEMBL767443
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Inhibition of Protein kinase C
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Syntheses and biological evaluation of indolocarbazoles, analogues of rebeccamycin, modified at the imide heterocycle.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.99 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3350555 | — | — | 1 | 5.43 |
| CHEMBL3350556 | — | — | 1 | 4.54 |
| CHEMBL3350558 | — | — | 1 | - |
| CHEMBL3350560 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3350555 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL3350556 | — | IC50 | = | 28800.0 | nM | 4.54 |
| CHEMBL3350558 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3350560 | — | IC50 | > | 100000.0 | nM | - |