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Assay Detail

CHEMBL767478

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of [3H]PDBU binding to protein kinase C mixture
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Protein kinase C (PKC) (CHEMBL2094266)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Conformationally constrained analogues of dag .8. Changes in PK-C binding affinity produced by isosteric groups of the 3-O-acyl function in 2-deoxy-L-ribonolactones
Lee J, Sharma R, Teng K, Lewin NE, Blumberg PM, Marquez VE
Bioorg Med Chem Lett (1994) 4 : 1369 -1374
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.60 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL276429 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL276429 Ki = 2500.0 nM 5.60