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Assay Detail

CHEMBL767844

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro inhibitory activity against prostacyclin synthetase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Prostacyclin synthase (CHEMBL4428)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Imidazo[1,5-a]pyridines: a new class of thromboxane A2 synthetase inhibitors.
Ford NF, Browne LJ, Campbell T, Gemenden C, Goldstein R, Gude C, Wasley JW.
J Med Chem (1985) 28 : 164 -170
PubMed 3918169 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.00 4.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL48092 PIRMAGREL 2.0 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL48092 PIRMAGREL IC50 = 100000.0 nM 4.00