Assay Detail
Binding
CHEMBL768159
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Compound was tested for inhibition of protein phosphatase 2A (PP2A)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
7-Oxa[2.2.1]bicycloheptane-2,3-dicarboxylic acid derivatives as phosphatase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.85 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48449 | CANTHARIDIN | 4.0 | 1 | 7.19 |
| CHEMBL314035 | — | — | 1 | 6.77 |
| CHEMBL315040 | — | — | 1 | 6.75 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48449 | CANTHARIDIN | Ki | = | 65.0 | nM | 7.19 |
| CHEMBL314035 | — | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL315040 | — | Ki | = | 180.0 | nM | 6.75 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | Ki | = | 200.0 | nM | 6.70 |