Assay Detail
Binding
CHEMBL768163
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Inhibition of protein phosphatase 2A (PP2A) was determined by standard phosphorylase inhibition assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.18 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL505512 | TAUTOMYCIN | — | 1 | 6.05 |
| CHEMBL40942 | — | — | 1 | 5.48 |
| CHEMBL289752 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL505512 | TAUTOMYCIN | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL40942 | — | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL289752 | — | IC50 | = | 100000.0 | nM | 4.00 |