Assay Detail
Binding
CHEMBL768165
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Observed inhibition activity of the compounds against protein phosphatases 2A (PP2A)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (CHEMBL4284) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A model for binding of structurally diverse natural product inhibitors of protein phosphatases PP1 and PP2A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 10.19 | 10.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL444092 | MICROCYSTIN-LR | — | 1 | 10.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL444092 | MICROCYSTIN-LR | IC50 | = | 0.065 | nM | 10.19 |