Assay Detail
Binding
CHEMBL768405
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Displacement of ATP from protein kinase C (PKC)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Design of potent protein kinase inhibitors using the bisubstrate approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.77 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL436718 | — | — | 1 | 7.00 |
| CHEMBL540848 | — | — | 1 | 5.22 |
| CHEMBL415414 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL436718 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL540848 | — | Ki | = | 6000.0 | nM | 5.22 |
| CHEMBL415414 | — | Ki | = | 8000.0 | nM | 5.10 |