Assay Detail
Binding
CHEMBL768488
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The compound was evaluated for its binding affinity against PAF receptor in human platelet
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.22 | 9.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL322832 | LEXIPAFANT | 2.0 | 1 | 9.42 |
| CHEMBL369225 | — | — | 1 | 9.24 |
| CHEMBL317090 | — | — | 1 | 9.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL322832 | LEXIPAFANT | Ki | = | 0.38 | nM | 9.42 |
| CHEMBL369225 | — | Ki | = | 0.57 | nM | 9.24 |
| CHEMBL317090 | — | Ki | = | 0.98 | nM | 9.01 |