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Assay Detail

CHEMBL768532

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of protein kinase C
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Protein kinase C (PKC) (CHEMBL2093867)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Secondary structure peptide mimetics: design, synthesis, and evaluation of beta-strand mimetic thrombin inhibitors.
Boatman PD, Ogbu CO, Eguchi M, Kim HO, Nakanishi H, Cao B, Shea JP, Kahn M.
J Med Chem (1999) 42 : 1367 -1375
PubMed 10212122 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.69 5.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL27852 1 5.90
CHEMBL282830 1 5.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL27852 IC50 = 1250.0 nM 5.90
CHEMBL282830 IC50 = 3320.0 nM 5.48