Assay Detail
Binding
CHEMBL769014
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Transcriptional activation for RXR alpha receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Structural basis for the differential RXR & RAR activity of stilbene retinoid analogs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.61 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL705 | ALITRETINOIN | 4.0 | 1 | 7.89 |
| CHEMBL36464 | — | — | 1 | 6.56 |
| CHEMBL284167 | — | — | 1 | 6.53 |
| CHEMBL32505 | — | — | 1 | 6.42 |
| CHEMBL284937 | — | — | 1 | 5.65 |
| CHEMBL2114394 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL705 | ALITRETINOIN | EC50 | = | 13.0 | nM | 7.89 |
| CHEMBL36464 | — | EC50 | = | 275.0 | nM | 6.56 |
| CHEMBL284167 | — | EC50 | = | 298.0 | nM | 6.53 |
| CHEMBL32505 | — | EC50 | = | 385.0 | nM | 6.42 |
| CHEMBL284937 | — | EC50 | = | 2220.0 | nM | 5.65 |
| CHEMBL2114394 | — | EC50 | > | 6400.0 | nM | - |