Assay Detail
Binding
CHEMBL769256
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Inhibitory activity against recombinant HIV-1 protease.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 protease (CHEMBL243) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Structure-based, C2 symmetric inhibitors of HIV protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.54 | 9.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL314298 | — | — | 1 | 9.66 |
| CHEMBL314758 | — | — | 1 | 9.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL314298 | — | IC50 | = | 0.22 | nM | 9.66 |
| CHEMBL314758 | — | IC50 | = | 0.38 | nM | 9.42 |