Assay Detail
Binding
CHEMBL769649
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Inhibitory concentration was measured against Cyclooxygenase-2 in human whole blood
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Blood |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
3,4-Diaryl-5-hydroxyfuranones: highly selective inhibitors of cyclooxygenase-2 with aqueous solubility.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.38 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18498 | — | — | 1 | 7.00 |
| CHEMBL18040 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18498 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL18040 | — | IC50 | = | 1800.0 | nM | 5.75 |