Assay Detail
Binding
CHEMBL769658
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and activity of a new methoxytetrahydropyran derivative as dual cyclooxygenase-2/5-lipoxygenase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL122 | ROFECOXIB | 4.0 | 1 | 9.00 |
| CHEMBL348825 | — | — | 1 | - |
| CHEMBL349370 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL122 | ROFECOXIB | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL348825 | — | IC50 | < | 100.0 | nM | - |
| CHEMBL349370 | — | IC50 | < | 100.0 | nM | - |