Assay Detail
Functional
CHEMBL769764
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Compound was tested for inhibition of LTB4 production by rat basophilic leukemia cells (RBL-1) stimulated with A-23187
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | RBL-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel naphthalene derivatives as inhibitors of human immunoglobulin E antibody production.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.04 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL130572 | — | — | 1 | 6.16 |
| CHEMBL423693 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL130572 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL423693 | — | IC50 | = | 1200.0 | nM | 5.92 |