Assay Detail
Binding
CHEMBL770262
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
cAMP-dependent protein kinase alpha-catalytic subunit (CHEMBL4885) ↗| Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
Publication
Neurotrophic 3,9-bis[(alkylthio)methyl]-and-bis(alkoxymethyl)-K-252a derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 10.80 | 10.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL281948 | K-252A | — | 1 | 10.80 |
| CHEMBL299496 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL281948 | K-252A | IC50 | = | 0.016 | nM | 10.80 |
| CHEMBL299496 | — | IC50 | > | 10.0 | nM | - |