Assay Detail
Binding
CHEMBL770292
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Displacement of [3H]phorbol-12,13-dibutyrate from mouse brain protein kinase C
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Conformationally constrained analogues of DAG.7. Interaction of a medium-size -lactone with protein kinase C (PK-C)_
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.24 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL276429 | — | — | 1 | 5.60 |
| CHEMBL311296 | — | — | 1 | 5.55 |
| CHEMBL13044 | — | — | 1 | 5.28 |
| CHEMBL150297 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL276429 | — | Ki | = | 2500.0 | nM | 5.60 |
| CHEMBL311296 | — | Ki | = | 2800.0 | nM | 5.55 |
| CHEMBL13044 | — | Ki | = | 5300.0 | nM | 5.28 |
| CHEMBL150297 | — | Ki | = | 30500.0 | nM | 4.52 |