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Assay Detail

CHEMBL770650

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for in vitro inhibition against broken RBL-1.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Cell Type RBL-1
Confidence 1 — Organism
Curated By Intermediate

Target

RBL-1 (CHEMBL614772)
Type CELL-LINE
Organism Rattus norvegicus

Publication

Modulators of leukotriene biosynthesis and receptor activation.
Brooks CD, Summers JB.
J Med Chem (1996) 39 : 2629 -2654
PubMed 8709092 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.46 7.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL59356 ATRELEUTON 2.0 1 7.64
CHEMBL90552 1 7.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL59356 ATRELEUTON IC50 = 23.0 nM 7.64
CHEMBL90552 IC50 = 54.0 nM 7.27