Assay Detail
Binding
CHEMBL771564
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Inhibition of His-tagged Protein kinase C epsilon over-expressed in COS7 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | COS-7 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.52 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7432 | — | — | 1 | 4.52 |
| CHEMBL7572 | — | — | 1 | - |
| CHEMBL7735 | — | — | 1 | - |
| CHEMBL7600 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7432 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL7572 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL7735 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL7600 | — | IC50 | > | 100000.0 | nM | - |