Assay Detail
Functional
CHEMBL772226
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Inhibitory concentration required against proliferation or inducing differentiation in the human chronic myelogenous leukemia cell line RWLeu4; active
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RWLeu4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
1-(hydroxyalkyl)-25-hydroxyvitamin D3 analogs of calcitriol. 2. Preliminary biological evaluation
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL55100 | — | — | 1 | 6.00 |
| CHEMBL52086 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL55100 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL52086 | — | IC50 | = | 1000.0 | nM | 6.00 |