Assay Detail
Functional
CHEMBL772310
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR beta
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CV-1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Enantioselective syntheses of potent retinoid X receptor ligands: differential biological activities of individual antipodes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.52 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL705 | ALITRETINOIN | 4.0 | 1 | 8.52 |
| CHEMBL308377 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL705 | ALITRETINOIN | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL308377 | — | EC50 | > | 500.0 | nM | - |