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Assay Detail

CHEMBL772396

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Effective concentration against RAR-alpha receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Retinoic acid receptor alpha (CHEMBL2055)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity.
Jong L, Lehmann JM, Hobbs PD, Harlev E, Huffman JC, Pfahl M, Dawson MI.
J Med Chem (1993) 36 : 2605 -2613
PubMed 8410972 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.62 6.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL284264 1 6.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL284264 EC50 = 240.0 nM 6.62