Assay Detail
Binding
CHEMBL795006
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Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductase; value ranges from 36-60 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human alphaherpesvirus 1 |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Ribonucleoside-diphosphate reductase RR1 (CHEMBL2095215) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Homo sapiens |
Publication
Synthesis and inhibitory potency of peptides corresponding to the subunit 2 C-terminal region of herpes virus ribonucleotide reductases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.44 | 4.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL430907 | — | — | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL430907 | — | IC50 | = | 36000.0 | nM | 4.44 |