Assay Detail
Binding
CHEMBL797917
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Binding affinity for human Retinoid X receptor RXR alpha
5
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Conformationally defined 6-s-trans-retinoic acid analogs. 2. Selective agonists for nuclear receptor binding and transcriptional activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 8.16 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL75548 | — | — | 1 | 8.52 |
| CHEMBL72988 | — | — | 1 | 7.80 |
| CHEMBL2111557 | — | — | 2 | - |
| CHEMBL46398 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL75548 | — | Kd | = | 3.0 | nM | 8.52 |
| CHEMBL72988 | — | Kd | = | 16.0 | nM | 7.80 |
| CHEMBL2111557 | — | Kd | > | 200.0 | nM | - |
| CHEMBL46398 | — | Kd | > | 200.0 | nM | - |
| CHEMBL2111557 | — | Kd | > | 200.0 | nM | - |