Assay Detail
Binding
CHEMBL798023
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Binding affinity towards Retinoic acid receptor gamma
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activities of new heterocyclic aromatic retinoids
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 6.82 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL75848 | — | — | 1 | 7.72 |
| CHEMBL25361 | — | — | 1 | 7.40 |
| CHEMBL1265 | ADAPALENE | 4.0 | 1 | 6.89 |
| CHEMBL75048 | — | — | 1 | 6.83 |
| CHEMBL75732 | — | — | 1 | 6.76 |
| CHEMBL74218 | — | — | 1 | 6.70 |
| CHEMBL308170 | — | — | 1 | 6.28 |
| CHEMBL75527 | — | — | 1 | 5.99 |
| CHEMBL75311 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL75848 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL25361 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL1265 | ADAPALENE | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL75048 | — | Ki | = | 148.0 | nM | 6.83 |
| CHEMBL75732 | — | Ki | = | 174.0 | nM | 6.76 |
| CHEMBL74218 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL308170 | — | Ki | = | 531.0 | nM | 6.28 |
| CHEMBL75527 | — | Ki | = | 1036.0 | nM | 5.99 |
| CHEMBL75311 | — | Ki | > | 3000.0 | nM | - |