Assay Detail
Binding
CHEMBL798069
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for inhibition of rat plasma renin at pH of 6.0.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Plasma |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.26 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2028991 | — | — | 1 | 7.58 |
| CHEMBL269752 | — | — | 1 | 6.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2028991 | — | Ki | = | 26.0 | nM | 7.58 |
| CHEMBL269752 | — | Ki | = | 115.0 | nM | 6.94 |