Assay Detail
Binding
CHEMBL798077
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Inhibition of [3H]9-cis-RA binding to human Retinoid X receptor RXR alpha
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 8.00 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89331 | — | — | 1 | 8.70 |
| CHEMBL89581 | — | — | 1 | 8.52 |
| CHEMBL88216 | — | — | 1 | 8.22 |
| CHEMBL705 | ALITRETINOIN | 4.0 | 1 | 8.10 |
| CHEMBL89058 | — | — | 1 | 7.80 |
| CHEMBL90674 | — | — | 1 | 7.39 |
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89331 | — | Kd | = | 2.0 | nM | 8.70 |
| CHEMBL89581 | — | Kd | = | 3.0 | nM | 8.52 |
| CHEMBL88216 | — | Kd | = | 6.0 | nM | 8.22 |
| CHEMBL705 | ALITRETINOIN | Kd | = | 8.0 | nM | 8.10 |
| CHEMBL89058 | — | Kd | = | 16.0 | nM | 7.80 |
| CHEMBL90674 | — | Kd | = | 41.0 | nM | 7.39 |
| CHEMBL38 | TRETINOIN | Kd | = | 53.0 | nM | 7.28 |