Assay Detail
Functional
CHEMBL798901
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective potency in transcriptional activation assay in CV-1 cells expressing retinoic acid receptor RAR beta
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CV-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and structure-activity relationships of potent retinoid X receptor ligands
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.25 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL79234 | — | — | 1 | 6.47 |
| CHEMBL312233 | — | — | 1 | 6.25 |
| CHEMBL80236 | — | — | 1 | 6.20 |
| CHEMBL312395 | — | — | 1 | 6.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL79234 | — | EC50 | = | 339.0 | nM | 6.47 |
| CHEMBL312233 | — | EC50 | = | 559.0 | nM | 6.25 |
| CHEMBL80236 | — | EC50 | = | 637.0 | nM | 6.20 |
| CHEMBL312395 | — | EC50 | = | 809.0 | nM | 6.09 |