Assay Detail
Binding
CHEMBL798951
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Time course of inactivation of bovine liver S-adenosyl-homocysteine hydrolase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.76 | 8.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8771 | NEOPLANOCIN A | — | 1 | 8.42 |
| CHEMBL147260 | — | — | 1 | 7.46 |
| CHEMBL299961 | — | — | 1 | 7.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8771 | NEOPLANOCIN A | Ki | = | 3.8 | nM | 8.42 |
| CHEMBL147260 | — | Ki | = | 35.0 | nM | 7.46 |
| CHEMBL299961 | — | Ki | = | 41.0 | nM | 7.39 |