Assay Detail
Binding
CHEMBL798952
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Evaluated for the 50% inhibition of bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 11. Molecular dissections of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.99 | 6.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298115 | — | — | 1 | 6.03 |
| CHEMBL296107 | — | — | 1 | 6.02 |
| CHEMBL46348 | — | — | 1 | 6.00 |
| CHEMBL50388 | — | — | 1 | 5.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298115 | — | IC50 | = | 930.0 | nM | 6.03 |
| CHEMBL296107 | — | IC50 | = | 950.0 | nM | 6.02 |
| CHEMBL46348 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL50388 | — | IC50 | = | 1230.0 | nM | 5.91 |