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Assay Detail

CHEMBL799566

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Transcriptional activation of Retinoid X receptor RXR alpha;NA=not active
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cercopithecidae
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Retinoic acid receptor RXR-alpha (CHEMBL2061)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid.
Beard RL, Colon DF, Song TK, Davies PJ, Kochhar DM, Chandraratna RA.
J Med Chem (1996) 39 : 3556 -3563
PubMed 8784454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.55 6.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL118693 1 6.55
CHEMBL324960 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL118693 EC50 = 280.0 nM 6.55
CHEMBL324960 EC50 - nM -