Assay Detail
Functional
CHEMBL799864
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alpha
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CV-1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.31 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98172 | — | — | 1 | 8.40 |
| CHEMBL1023 | BEXAROTENE | 4.0 | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98172 | — | EC50 | = | 4.0 | nM | 8.40 |
| CHEMBL1023 | BEXAROTENE | EC50 | = | 6.0 | nM | 8.22 |