Assay Detail
Binding
CHEMBL799875
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Binding affinity for baculovirus-expressed Retinoic acid receptor RAR alpha
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Identification of a retinoic acid receptor alpha subtype specific agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 7.77 | 8.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL317873 | — | — | 1 | 8.36 |
| CHEMBL439780 | — | — | 1 | 8.08 |
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 7.82 |
| CHEMBL69367 | — | — | 1 | 7.44 |
| CHEMBL86663 | — | — | 1 | 7.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL317873 | — | Kd | = | 4.4 | nM | 8.36 |
| CHEMBL439780 | — | Kd | = | 8.4 | nM | 8.08 |
| CHEMBL38 | TRETINOIN | Kd | = | 15.0 | nM | 7.82 |
| CHEMBL69367 | — | Kd | = | 36.0 | nM | 7.44 |
| CHEMBL86663 | — | Kd | = | 72.0 | nM | 7.14 |