Assay Detail
Binding
CHEMBL800046
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Inhibitory effect on HIV-1 RT activity using template primer,poly (rC)-oligo (dG)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 protease (CHEMBL243) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Thiadiazole derivatives: highly potent and specific HIV-1 reverse transcriptase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.31 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL62196 | — | — | 1 | 6.52 |
| CHEMBL60314 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL62196 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL60314 | — | IC50 | = | 800.0 | nM | 6.10 |