Assay Detail
Binding
CHEMBL800353
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Antagonist binding of N6-cyclohexyl-[3H]-adenosine to rat testes
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Testis |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Expert |
Publication
Adenosine receptors: targets for future drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.72 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL45891 | — | — | 1 | 8.85 |
| CHEMBL139000 | (R)-PIA | — | 1 | 8.85 |
| CHEMBL420705 | (S)-PIA | — | 1 | 6.96 |
| CHEMBL1355736 | THEOPHYLLINE | 4.0 | 1 | 4.70 |
| CHEMBL113 | CAFFEINE | 4.0 | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL45891 | — | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL139000 | (R)-PIA | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL420705 | (S)-PIA | Ki | = | 110.0 | nM | 6.96 |
| CHEMBL1355736 | THEOPHYLLINE | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL113 | CAFFEINE | Ki | = | 60000.0 | nM | 4.22 |