Assay Detail
Binding
CHEMBL800528
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of purified recombinant human placental S-adenosyl-homocysteine hydrolase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis, mechanism of action, and antiviral activity of a new series of covalent mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.65 | 4.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL607985 | — | — | 1 | 4.80 |
| CHEMBL606446 | — | — | 1 | 4.80 |
| CHEMBL140440 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL607985 | — | Ki | = | 16000.0 | nM | 4.80 |
| CHEMBL606446 | — | Ki | = | 16000.0 | nM | 4.80 |
| CHEMBL140440 | — | Ki | = | 45000.0 | nM | 4.35 |