Assay Detail
Binding
CHEMBL800623
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Inhibitory activity against recombinant rat liver S-adenosyl-homocysteine hydrolase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.40 | 7.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL171700 | — | — | 1 | 7.41 |
| CHEMBL77518 | — | — | 1 | 7.41 |
| CHEMBL171369 | — | — | 1 | 7.40 |
| CHEMBL308037 | — | — | 1 | 7.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL171700 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL77518 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL171369 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL308037 | — | Ki | = | 43.0 | nM | 7.37 |