Assay Detail
Binding
CHEMBL800629
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibitory concentration against S-adenosyl-homocysteine hydrolase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
()-7-deazaaristeromycin lacking the hydroxymethyl substituent
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.49 | 8.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8771 | NEOPLANOCIN A | — | 1 | 8.14 |
| CHEMBL281337 | — | — | 1 | 7.75 |
| CHEMBL284846 | 3-DEAZANEPLANOCIN A | — | 1 | 7.51 |
| CHEMBL494759 | (S)-DHPA | — | 1 | 6.55 |
| CHEMBL160308 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8771 | NEOPLANOCIN A | IC50 | = | 7.2 | nM | 8.14 |
| CHEMBL281337 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL284846 | 3-DEAZANEPLANOCIN A | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL494759 | (S)-DHPA | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL160308 | — | IC50 | > | 100000.0 | nM | - |