Assay Detail
Functional
CHEMBL800729
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Compound was evaluated for cytotoxicity against SCOV-3 cell lines.
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel imidazothioxanthones: Synthesis, DNA binding and cytotoxicity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.56 | 8.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL58 | MITOXANTRONE | 4.0 | 1 | 8.28 |
| CHEMBL353282 | — | — | 1 | 5.78 |
| CHEMBL171004 | — | — | 1 | 5.67 |
| CHEMBL169245 | — | — | 1 | 5.11 |
| CHEMBL171056 | — | — | 1 | 4.87 |
| CHEMBL172337 | — | — | 1 | 4.64 |
| CHEMBL171026 | — | — | 1 | 4.54 |
| CHEMBL434104 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL58 | MITOXANTRONE | IC50 | = | 5.3 | nM | 8.28 |
| CHEMBL353282 | — | IC50 | = | 1650.0 | nM | 5.78 |
| CHEMBL171004 | — | IC50 | = | 2150.0 | nM | 5.67 |
| CHEMBL169245 | — | IC50 | = | 7700.0 | nM | 5.11 |
| CHEMBL171056 | — | IC50 | = | 13500.0 | nM | 4.87 |
| CHEMBL172337 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL171026 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL434104 | — | IC50 | > | 100000.0 | nM | - |