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Assay Detail

CHEMBL801065

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro inhibition of Human plasma renin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Tissue Plasma
Confidence 9 — Direct single protein target
Curated By Expert

Target

Renin (CHEMBL286)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and biological activity of some transition-state inhibitors of human renin.
Bühlmayer P, Caselli A, Fuhrer W, Göschke R, Rasetti V, Rüeger H, Stanton JL, Criscione L, Wood JM.
J Med Chem (1988) 31 : 1839 -1846
PubMed 3137345 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.70 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL53139 1 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL53139 IC50 = 2.0 nM 8.70