Assay Detail
Functional
CHEMBL801111
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Compound was tested for the growth inhibition of SW-620 colon tumor cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW-620 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiparasitic and antitumor activity of 2, 4-diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.25 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7375 | — | — | 1 | 6.50 |
| CHEMBL267616 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7375 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL267616 | — | IC50 | = | 990.0 | nM | 6.00 |