Assay Detail
Functional
CHEMBL801128
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In Vitro cell growth inhibitory activity of CNDAC against Small Cell Lung Carcinoma-5 (2.5*10e2) cells on 48-h exposure
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SBC-5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.54 | 6.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL337450 | TAS-109 | 2.0 | 2 | 6.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL337450 | TAS-109 | IC50 | = | 222.0 | nM | 6.65 |
| CHEMBL337450 | TAS-109 | IC50 | = | 367.0 | nM | 6.43 |