Assay Detail
Functional
CHEMBL801130
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for its inhibitory activity against SBC-5 human lung cancer cell line
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SBC-5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of the novel analogues of dysidiolide and their structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.25 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86406 | — | — | 1 | 5.89 |
| CHEMBL313595 | — | — | 1 | 5.36 |
| CHEMBL1765353 | DYSIDIOLIDE | — | 1 | 5.27 |
| CHEMBL86451 | — | — | 1 | 4.92 |
| CHEMBL356927 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86406 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL313595 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL1765353 | DYSIDIOLIDE | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL86451 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL356927 | — | IC50 | = | 16000.0 | nM | 4.80 |