Assay Detail
Binding
CHEMBL801133
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Compound was evaluated for the inhibition of SBL-M222C-SEtSO3- enzyme.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Lederbergia lenta |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Altering the specificity of subtilisin B. Lentus by combining site-directed mutagenesis and chemical modification
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 4.79 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20726 | — | — | 1 | 4.96 |
| CHEMBL20866 | — | — | 1 | 4.81 |
| CHEMBL20421 | — | — | 1 | 4.60 |
| CHEMBL20461 | PHENETHYLBORONIC ACID | — | 1 | - |
| CHEMBL20852 | — | — | 1 | - |
| CHEMBL21485 | PHENYLBORONIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20726 | — | Ki | = | 11000.0 | nM | 4.96 |
| CHEMBL20866 | — | Ki | = | 15600.0 | nM | 4.81 |
| CHEMBL20421 | — | Ki | = | 25000.0 | nM | 4.60 |
| CHEMBL20461 | PHENETHYLBORONIC ACID | Ki | = | 290000.0 | nM | - |
| CHEMBL20852 | — | Ki | = | 176000.0 | nM | - |
| CHEMBL21485 | PHENYLBORONIC ACID | Ki | = | 146000.0 | nM | - |