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Assay Detail

CHEMBL801190

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibitory activity of compound for 96-h exposure in SKOV-3 cell line
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SK-OV-3
Confidence 1 — Organism
Curated By Intermediate

Target

SK-OV-3 (CHEMBL614925)
Type CELL-LINE
Organism Homo sapiens

Publication

A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.
Mann J, Baron A, Opoku-Boahen Y, Johansson E, Parkinson G, Kelland LR, Neidle S.
J Med Chem (2001) 44 : 138 -144
PubMed 11170623 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL34618 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL34618 IC50 = 100.0 nM 7.00