Assay Detail

CHEMBL801735

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Functional

Tested for effect to cause relaxation of renal mesenteric artery previously contracted by PGF2-alpha

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

10,10-Difluoro-13-dehydroprostacyclin: a chemically and metabolically stabilized potent prostacyclin.

Fried J, Mitra DK, Nagarajan M, Mehrotra MM.
J Med Chem (1980) 23 : 234 -237
PubMed 6988588 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.48	8.48

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1139	EPOPROSTENOL	4.0	1	8.48

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1139	EPOPROSTENOL	EC50	=	3.3	nM	8.48