Assay Detail
Binding
CHEMBL801746
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Compound was tested for the inhibition of monkey plasma renin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cercopithecidae |
| Tissue | Plasma |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Preparation of a novel series of phosphonate norstatine renin inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.50 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL59973 | — | — | 1 | 9.70 |
| CHEMBL60550 | TERLAKIREN | 2.0 | 1 | 9.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL59973 | — | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL60550 | TERLAKIREN | IC50 | = | 0.5 | nM | 9.30 |